| Long name: |
Biotin Conjugated, RSK3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RSK3 |
| Specificity: |
This is a highly specific antibody against RSK3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human RSK3/Ribosomal S6 kinase 3 |
| Gene ID number: |
6196 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB, Rsk2 and Rsk3, Rsk3 is a distinct isoform of p90Rsk that translocates to the cell nucleus, Ser363 and Thr573, Several sites, These are broadly expressed serine/threonine protein kinases that are activated in response to mitogenic stimuli, Thr359, are important for its activation, including extracellular signal-regulated protein kinases Erk1 and Erk2, phosphorylates potential nuclear targets and may have a unique upstream activator, such as Ser380, which includes Rsk1, RSK3(Ribosomal S6 kinase 3)is a member of a family of 90-kDa ribosomal protein S6 kinases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
RSK RSK3 HU-2 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RSK3 Conjugated |
| Short name: |
Conjugated, RSK3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, RSK3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10431 |
| Gene: |
RPS6KA2 |
More about : RPS6KA2 |
| Long gene name: |
ribosomal protein S6 kinase A2 |
| Synonyms gene name: |
90kD, polypeptide 2 , ribosomal protein S6 kinase |
| Locus: |
6q27 |
| Discovery year: |
1994-07-11 |
| GenBank acession: |
L07598 |
| Entrez gene record: |
6196 |
| Pubmed identfication: |
8141249 |
| RefSeq identity: |
NM_021135 |
| Classification: |
Mitogen-activated protein kinase-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000016007 |