| Long name: |
FITC Conjugated, Torc1 (Ser151) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Torc1 Ser151 |
| Specificity: |
Due to the highly conserved nature of this protein, this antibody will react with Torc3 when phosphorylated at Ser162 across the listed species due to homology, This is a highly specific antibody against Torc1 Ser151 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser151 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
125-175/634 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Torc1 around the phosphorylation site of Ser151 |
| Gene ID number: |
23373 |
| Swiss Prot: |
Q6UUV9 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a coactivator, Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR), Enhances the interaction of CREB1 with TAF4, In concert with SIK1, In response to light stimulus, In the hippocampus, May be required for dendritic growth of developing cortical neurons (By similarity), Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells, Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock, in the SIK/TORC signaling pathway, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses, regulates the light-induced entrainment of the circadian clock, Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CREB-regulated transcription coactivator 1, CRTC1, KIAA0616, Mucoepidermoid carcinoma translocated protein 1, TORC-1, TORC1, Transducer of CREB protein 1, Transducer of regulated cAMP response element-binding protein 1, WAMTP1, MECT1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Torc1 (Ser151) Conjugated |
| Short name: |
FITC Conjugated, Torc1 (Ser151) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Torc1 (Ser151) (Antibody to) |
| Alternative technique: |
antibodies |