| Long name: |
Cy3 Conjugated, Torc1 (Ser151) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Torc1 Ser151 |
| Specificity: |
Due to the highly conserved nature of this protein, this antibody will react with Torc3 when phosphorylated at Ser162 across the listed species due to homology, This is a highly specific antibody against Torc1 Ser151 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser151 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
125-175/634 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Torc1 around the phosphorylation site of Ser151 |
| Gene ID number: |
23373 |
| Swiss Prot: |
Q6UUV9 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a coactivator, Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR), Enhances the interaction of CREB1 with TAF4, In concert with SIK1, In response to light stimulus, In the hippocampus, May be required for dendritic growth of developing cortical neurons (By similarity), Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells, Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock, in the SIK/TORC signaling pathway, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses, regulates the light-induced entrainment of the circadian clock, Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
CREB-regulated transcription coactivator 1, CRTC1, KIAA0616, Mucoepidermoid carcinoma translocated protein 1, TORC-1, TORC1, Transducer of CREB protein 1, Transducer of regulated cAMP response element-binding protein 1, WAMTP1, MECT1 |
| Properties: |
1 of the Torc1 (Ser151) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Torc1 (Ser151) Conjugated |
| Short name: |
Conjugated, Torc1 (Ser151) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, Torc1 (Ser151) (Antibody to) |
| Alternative technique: |
antibodies |