| Long name: |
Biotin Conjugated, Torc1 (Ser151) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Torc1 Ser151 |
| Specificity: |
Due to the highly conserved nature of this protein, this antibody will react with Torc3 when phosphorylated at Ser162 across the listed species due to homology, This is a highly specific antibody against Torc1 Ser151 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser151 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
125-175/634 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Torc1 around the phosphorylation site of Ser151 |
| Gene ID number: |
23373 |
| Swiss Prot: |
Q6UUV9 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a coactivator, Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR), Enhances the interaction of CREB1 with TAF4, In concert with SIK1, In response to light stimulus, In the hippocampus, May be required for dendritic growth of developing cortical neurons (By similarity), Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells, Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock, in the SIK/TORC signaling pathway, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses, regulates the light-induced entrainment of the circadian clock, Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CREB-regulated transcription coactivator 1, CRTC1, KIAA0616, Mucoepidermoid carcinoma translocated protein 1, TORC-1, TORC1, Transducer of CREB protein 1, Transducer of regulated cAMP response element-binding protein 1, WAMTP1, MECT1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Torc1 (Ser151) Conjugated |
| Short name: |
Conjugated, Torc1 (Ser151) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Torc1 (Ser151) (Antibody to) |
| Alternative technique: |
antibodies |