| Long name: |
ALEXA FLUOR 488 Conjugated, Torc1 (Ser151) Polyclonal Antibody |
| Also known as: |
Anti-Torc1 Ser151 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Torc1 Ser151 |
| Specificity: |
This is a highly specific antibody against Torc1 Ser151 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser151 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
125-175/634 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Torc1 around the phosphorylation site of Ser151 |
| Gene ID Number: |
23373 |
| Swiss Prot: |
Q6UUV9 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts as a coactivator, Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR), Enhances the interaction of CREB1 with TAF4, In concert with SIK1, In response to light stimulus, In the hippocampus, May be required for dendritic growth of developing cortical neurons (By similarity), Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells, Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock, in the SIK/TORC signaling pathway, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses, regulates the light-induced entrainment of the circadian clock, Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CREB-regulated transcription coactivator 1, CRTC1, KIAA0616, Mucoepidermoid carcinoma translocated protein 1, TORC-1, TORC1, Transducer of CREB protein 1, Transducer of regulated cAMP response element-binding protein 1, WAMTP1, MECT1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Torc1 (Ser151) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Torc1 (Ser151) |
| Short name: |
Torc1 (Ser151) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Torc1 (Ser151) (Antibody to) |
| Alternative technique: |
antibodies |