| Long name: |
FITC Conjugated, TORC2 (Ser171) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TORC2 Ser171 |
| Specificity: |
This is a highly specific antibody against TORC2 Ser171 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser171 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
150-190/693 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171 |
| Gene ID number: |
200186 |
| Swiss Prot: |
Q53ET0 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a coactivator, Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR), Enhances the interaction of CREB1 with TAF4, Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells, Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway, Regulates the expression of specific genes such as the steroidogenic gene, StAR, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation, in the SIK/TORC signaling pathway, Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
TORC2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TORC2 (Ser171) Conjugated |
| Short name: |
FITC Conjugated, TORC2 (Ser171) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TORC2 (Ser171) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
27301 |
| Gene: |
CRTC2 |
More about : CRTC2 |
| Long gene name: |
CREB regulated transcription coactivator 2 |
| Locus: |
1q21, 3 |
| Discovery year: |
2005-11-24 |
| GenBank acession: |
AY360172 |
| Entrez gene record: |
200186 |
| Pubmed identfication: |
14506290 14536081 |
| RefSeq identity: |
NM_181715 |
| Havana BLAST/BLAT: |
OTTHUMG00000037156 |