| Long name: |
Cy3 Conjugated, TORC2 (Ser171) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TORC2 Ser171 |
| Specificity: |
This is a highly specific antibody against TORC2 Ser171 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser171 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
150-190/693 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171 |
| Gene ID number: |
200186 |
| Swiss Prot: |
Q53ET0 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a coactivator, Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR), Enhances the interaction of CREB1 with TAF4, Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells, Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway, Regulates the expression of specific genes such as the steroidogenic gene, StAR, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation, in the SIK/TORC signaling pathway, Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
TORC2 |
| Properties: |
1 of the TORC2 (Ser171) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TORC2 (Ser171) Conjugated |
| Short name: |
Conjugated, TORC2 (Ser171) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, TORC2 (Ser171) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
27301 |
| Gene: |
CRTC2 |
More about : CRTC2 |
| Long gene name: |
CREB regulated transcription coactivator 2 |
| Locus: |
1q21, 3 |
| Discovery year: |
2005-11-24 |
| GenBank acession: |
AY360172 |
| Entrez gene record: |
200186 |
| Pubmed identfication: |
14506290 14536081 |
| RefSeq identity: |
NM_181715 |
| Havana BLAST/BLAT: |
OTTHUMG00000037156 |