| Long name: |
ALEXA FLUOR 488 Conjugated, TORC2 (Ser171) Polyclonal Antibody |
| Also known as: |
Anti-TORC2 Ser171 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TORC2 Ser171 |
| Specificity: |
This is a highly specific antibody against TORC2 Ser171 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser171 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
150-190/693 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171 |
| Gene ID Number: |
200186 |
| Swiss Prot: |
Q53ET0 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts as a coactivator, Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR), Enhances the interaction of CREB1 with TAF4, Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells, Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway, Regulates the expression of specific genes such as the steroidogenic gene, StAR, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation, in the SIK/TORC signaling pathway, Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
TORC2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TORC2 (Ser171) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TORC2 (Ser171) |
| Short name: |
TORC2 (Ser171) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, TORC2 (Ser171) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
27301 |
| Gene: |
CRTC2 |
More about : CRTC2 |
| Long gene name: |
CREB regulated transcription coactivator 2 |
| Locus: |
1q21, 3 |
| Discovery year: |
2005-11-24 |
| GenBank acession: |
AY360172 |
| Entrez gene record: |
200186 |
| Pubmed identfication: |
14506290 14536081 |
| RefSeq identity: |
NM_181715 |
| Havana BLAST/BLAT: |
OTTHUMG00000037156 |