Jak3 (Tyr980 + Tyr981) Antibody, ALEXA FLUOR 647

Catalog number:	bs-3208R-A647 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	Jak3 (Tyr980 + Tyr981) Antibody, ALEXA FLUOR 647
Quantity:	100ul
Related search:	tyr jak alexa fluor ilr antibodies conjugated kinase alternative development

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Long name:	ALEXA FLUOR 647 Conjugated, Jak3 (Tyr980 + Tyr981) Antibody
Also known as:	Anti-Jak3 Tyr980 + Tyr981 PAb ALEXA FLUOR 647
Category:	Conjugated Primary Antibodies
Conjugated with:	647, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Jak3 Tyr980 + Tyr981
Specificity:	This is a highly specific antibody against Jak3 Tyr980 + Tyr981
Modification:	Phosphorylation
Modification Site:	Tyr980 + Tyr981
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	971-990/1124
Subcellular location:	Cell membrane, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human Jak3 around the phosphorylation site of Tyr980/981
Gene ID Number:	3718
Swiss Prot:	P52333
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Following ligand binding to cell surface receptors, For example, IL15R and IL21R, IL4R, IL7R, IL9R, In the cytoplasm, JAK1 and JAK3 molecules bind to IL2R beta (IL2RB) and gamma chain (IL2RG) subunits inducing the tyrosine phosphorylation of both receptor subunits on their cytoplasmic domain, Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development, Once activated, Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription, STAT5A AND STAT5B are recruited, Subsequently, Then, creating docking sites for STATs proteins, development, dimerized STAT5 translocates to the nucleus and promotes the transcription of specific target genes in a cytokine-specific fashion, or differentiation, phosphorylated and activated by JAK1 and JAK3, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, phosphorylates the STATs proteins once they are recruited to the receptor, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, upon IL2R activation by IL2, Non-receptor tyrosine kinase involved in various processes such as cell growth
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	650nm/665nm
Synonyms:	JAK-3, JAK3, JAK3_HUMAN, Janus kinase 3, L-JAK, LJAK, Leukocyte janus kinase, Tyrosine-protein kinase JAK3, JAKL
Properties:	ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Jak3 (Tyr980 + Tyr981) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 647, Alexa Fluor
Gene target:	Jak3 (Tyr980 + Tyr981)
Short name:	Jak3 (Tyr980 + Tyr981) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 647
Alternative name:	ALEXA FLUOR 647, Janus kinase 3 (Tyr980 and Tyr981) (Antibody to)
Alternative technique:	antibodies

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