Aurora A (Thr288) Antibody, Biotin Conjugated

Catalog number:	bs-3050R-Biotin Buy Now
Price:	516 €
Supplier:	Bioss Polyclonal Antibodies
Product name:	Aurora A (Thr288) Antibody, Biotin Conjugated
Quantity:	100 microliters
Related search:	antibody kinase biotin this serinethreonineprotein formation

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Long name:	Biotin Conjugated, Aurora A (Thr288) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Aurora A Thr288
Specificity:	This antibody may detect this protein in mouse when phosphorylated at Thr279, This phosphorylation site is homologous to that of Thr281 in Rat, but at a reduced affinity due to a single amino acid change in the immunogen, This is a highly specific antibody against Aurora A Thr288
Modification:	Phosphorylation
Modification site:	Thr288
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	260-300/403
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human Aurora A around the phosphorylation site of Thr288
Gene ID number:	6790
Swiss Prot:	O14965
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Also acts as a key regulatory component of the p53/TP53 pathway, Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, BORA, BRCA1, CDC25B, DLGP5, HDAC6, Important for microtubule formation and/or stabilization, KIF2A, LATS2, NDEL1, Necessary for proper cilia disassembly prior to mitosis, PARD3, PLK1, PPP1R2, Phosphorylates its own inhibitors, Phosphorylates numerous target proteins, Plays a role in microtubule remodeling during neurite extension, RASSF1, Regulates KIF2A tubulin depolymerase activity, Required for initial activation of CDK1 at centrosomes, Required for normal axon formation, TACC3, and cytokinesis, and particularly the checkpoint-response pathways critical for oncogenic transformation of cells, by phosphorylating and stabilizing p53/TP53, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, including ARHGEF2, p53/TP53 and TPX2, spindle assembly checkpoint, the protein phosphatase type 1 (PP1) isoforms, to inhibit their activity, Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	AIRK1, ARK-1, ARK1, AURA, AURKA, AURORA2, AYK1, Aurora 2, Aurora kinase A, Aurora-related kinase 1, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, IAK1, PPP1R47, STK15, STK6, STK7, Serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, Serine/threonine-protein kinase aurora-A, hARK1, AIK
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	Aurora A (Thr288) Conjugated
Short name:	Conjugated, Aurora A (Thr288) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, Aurora A (Thr288) (Antibody to)
Alternative technique:	antibodies

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