| Long name: |
ALEXA FLUOR 647 Conjugated, Aurora A (Thr288) Polyclonal Antibody |
| Also known as: |
Anti-Aurora A Thr288 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Aurora A Thr288 |
| Specificity: |
This is a highly specific antibody against Aurora A Thr288 |
| Modification: |
Phosphorylation |
| Modification Site: |
Thr288 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
260-300/403 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Aurora A around the phosphorylation site of Thr288 |
| Gene ID Number: |
6790 |
| Swiss Prot: |
O14965 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Also acts as a key regulatory component of the p53/TP53 pathway, Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, BORA, BRCA1, CDC25B, DLGP5, HDAC6, Important for microtubule formation and/or stabilization, KIF2A, LATS2, NDEL1, Necessary for proper cilia disassembly prior to mitosis, PARD3, PLK1, PPP1R2, Phosphorylates its own inhibitors, Phosphorylates numerous target proteins, Plays a role in microtubule remodeling during neurite extension, RASSF1, Regulates KIF2A tubulin depolymerase activity, Required for initial activation of CDK1 at centrosomes, Required for normal axon formation, TACC3, and cytokinesis, and particularly the checkpoint-response pathways critical for oncogenic transformation of cells, by phosphorylating and stabilizing p53/TP53, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, including ARHGEF2, p53/TP53 and TPX2, spindle assembly checkpoint, the protein phosphatase type 1 (PP1) isoforms, to inhibit their activity, Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
AIRK1, ARK-1, ARK1, AURA, AURKA, AURORA2, AYK1, Aurora 2, Aurora kinase A, Aurora-related kinase 1, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, IAK1, PPP1R47, STK15, STK6, STK7, Serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, Serine/threonine-protein kinase aurora-A, hARK1, AIK |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Aurora A (Thr288) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Aurora A (Thr288) |
| Short name: |
Aurora A (Thr288) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Aurora A (Thr288) (Antibody to) |
| Alternative technique: |
antibodies |