ASK1 (Thr845) Antibody, Biotin Conjugated

Catalog number:	bs-3031R-Biotin Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	ASK1 (Thr845) Antibody, Biotin Conjugated
Quantity:	0.1ml
Related search:	kinase thr gene signal transduction protein synonyms plays

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Long name:	Biotin Conjugated, ASK1 (Thr845) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	ASK1 Thr845
Specificity:	This is a highly specific antibody against ASK1 Thr845
Modification:	Phosphorylation
Modification site:	Thr845
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	825-875/1380
Subcellular location:	Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from mouse ASK1 around the phosphorylation site of Thr845
Gene ID number:	26408
Swiss Prot:	O35099
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Both p38 MAPK and JNKs control the transcription factors activator protein-1 (AP-1), MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7, MAP3K5/ASK1 is required for the innate immune response, Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, Mediates signaling for determination of cell fate such as differentiation and survival, Once activated, Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation, Plays an important role in the cascades of cellular responses evoked by changes in the environment, These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs), acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K4/SEK1, such as the tumor necrosis factor (TNF) or lipopolysaccharide (LPS), which is essential for host defense against a wide range of pathogens, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	MAPKKK5 ASK1
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	ASK1 (Thr845) Conjugated
Short name:	Conjugated, ASK1 (Thr845) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, ASK1 (Thr845) (Antibody to)
Alternative technique:	antibodies
Identity:	6857
Gene:	MAP3K5 | More about : MAP3K5
Long gene name:	mitogen-activated protein kinase kinase kinase 5
Synonyms gene:	MEKK5
Synonyms name:	apoptosis signal regulating kinase 1
Locus:	6q23, 3
Discovery year:	1997-11-14
GenBank acession:	U67156
Entrez gene record:	4217
Pubmed identfication:	9465908
Classification:	Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT:	OTTHUMG00000015647
Locus Specific Databases:	The Globin Gene Server

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