ASK1 (Thr845) Antibody, Cy5.5 Conjugated

Catalog number:	bs-3031R-Cy5.5 Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	ASK1 (Thr845) Antibody, Cy5.5 Conjugated
Quantity:	0.1ml
Related search:	kinase antibodies gene signal transduction protein synonyms apoptosis

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Long name:	Cy5, 5 Conjugated, ASK1 (Thr845) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Cy5, 5, 5, Cy5
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	ASK1 Thr845
Specificity:	This is a highly specific antibody against ASK1 Thr845
Modification:	Phosphorylation
Modification site:	Thr845
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	825-875/1380
Subcellular location:	Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from mouse ASK1 around the phosphorylation site of Thr845
Gene ID number:	26408
Swiss Prot:	O35099
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Both p38 MAPK and JNKs control the transcription factors activator protein-1 (AP-1), MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7, MAP3K5/ASK1 is required for the innate immune response, Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, Mediates signaling for determination of cell fate such as differentiation and survival, Once activated, Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation, Plays an important role in the cascades of cellular responses evoked by changes in the environment, These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs), acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K4/SEK1, such as the tumor necrosis factor (TNF) or lipopolysaccharide (LPS), which is essential for host defense against a wide range of pathogens, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	675nm/694nm
Synonyms:	MAPKKK5 ASK1
Properties:	Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated:	These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene target:	ASK1 (Thr845) Conjugated
Short name:	Conjugated, ASK1 (Thr845) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	5, Cy5
Alternative name:	cyanine 5, 5 coupled, ASK1 (Thr845) (Antibody to)
Alternative technique:	antibodies
Identity:	6857
Gene:	MAP3K5 | More about : MAP3K5
Long gene name:	mitogen-activated protein kinase kinase kinase 5
Synonyms gene:	MEKK5
Synonyms name:	apoptosis signal regulating kinase 1
Locus:	6q23, 3
Discovery year:	1997-11-14
GenBank acession:	U67156
Entrez gene record:	4217
Pubmed identfication:	9465908
Classification:	Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT:	OTTHUMG00000015647
Locus Specific Databases:	The Globin Gene Server

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