| Long name: |
Biotin Conjugated, GPNMB Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPNMB |
| Specificity: |
This is a highly specific antibody against GPNMB |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
85-135/572 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GPNMB |
| Gene ID number: |
10457 |
| Swiss Prot: |
Q14956 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
GPNMB may be involved in growth delay and reduction of metastatic potential, GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines, Two transcript variants encoding different isoforms have been found for this gene, [provided by RefSeq], a melanocyte-specific protein, The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
NMB HGFIN |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPNMB Conjugated |
| Short name: |
Conjugated, GPNMB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, glycoprotein (transmembrane) nmb (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, GPNMB and IDBG-9627 and ENSG00000136235 and 10457, Gpnmb and IDBG-146080 and ENSMUSG00000029816 and 93695, HGFIN and NMB, Plasma membranes, heparin binding, this GO :0001649 and osteoblast differentiation and biological process this GO :0005178 and integrin binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0008201 and heparin binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0030282 and bone mineralization and biological process this GO :0042470 and melanosome and cellular component, this GO :0005178 : integrin binding, this GO :0005178 : integrin binding and also this GO :0008201 : heparin binding, this GO :0008201 : heparin binding, 99652 and IDBG-630320 and ENSBTAG00000000604 and 509600, glycoprotein (transmembrane) nmb |
| Identity: |
4462 |
| Gene: |
GPNMB |
More about : GPNMB |
| Long gene name: |
glycoprotein nmb |
| Synonyms gene name: |
glycoprotein (transmembrane) nmb |
| Synonyms name: |
transmembrane glycoprotein glycoprotein NMB glycoprotein nmb-like protein osteoactivin hematopoietic growth factor inducible neurokinin-1 glycoprotein nonmetastatic melanoma protein B |
| Locus: |
7p15, 3 |
| Discovery year: |
1999-10-26 |
| GenBank acession: |
X76534 |
| Entrez gene record: |
10457 |
| Pubmed identfication: |
7814155 |
| RefSeq identity: |
NM_001005340 |
| Havana BLAST/BLAT: |
OTTHUMG00000022811 |