| Long name: |
ALEXA FLUOR 488 Conjugated, GPNMB Polyclonal Antibody |
| Also known as: |
Anti-GPNMB PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPNMB |
| Specificity: |
This is a highly specific antibody against GPNMB |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
85-135/572 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPNMB |
| Gene ID Number: |
10457 |
| Swiss Prot: |
Q14956 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
GPNMB may be involved in growth delay and reduction of metastatic potential, GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines, Two transcript variants encoding different isoforms have been found for this gene, [provided by RefSeq], a melanocyte-specific protein, The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
NMB HGFIN |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GPNMB Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
GPNMB |
| Short name: |
GPNMB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, glycoprotein (transmembrane) nmb (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, GPNMB and IDBG-9627 and ENSG00000136235 and 10457, Gpnmb and IDBG-146080 and ENSMUSG00000029816 and 93695, HGFIN and NMB, Plasma membranes, heparin binding, this GO :0001649 and osteoblast differentiation and biological process this GO :0005178 and integrin binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0008201 and heparin binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0030282 and bone mineralization and biological process this GO :0042470 and melanosome and cellular component, this GO :0005178 : integrin binding, this GO :0005178 : integrin binding and also this GO :0008201 : heparin binding, this GO :0008201 : heparin binding, 99652 and IDBG-630320 and ENSBTAG00000000604 and 509600, glycoprotein (transmembrane) nmb |
| Identity: |
4462 |
| Gene: |
GPNMB |
More about : GPNMB |
| Long gene name: |
glycoprotein nmb |
| Synonyms gene name: |
glycoprotein (transmembrane) nmb |
| Synonyms name: |
transmembrane glycoprotein glycoprotein NMB glycoprotein nmb-like protein osteoactivin hematopoietic growth factor inducible neurokinin-1 glycoprotein nonmetastatic melanoma protein B |
| Locus: |
7p15, 3 |
| Discovery year: |
1999-10-26 |
| GenBank acession: |
X76534 |
| Entrez gene record: |
10457 |
| Pubmed identfication: |
7814155 |
| RefSeq identity: |
NM_001005340 |
| Havana BLAST/BLAT: |
OTTHUMG00000022811 |