| Long name: |
ALEXA FLUOR 488 Conjugated, Cathepsin C/DPP1 Polyclonal Antibody |
| Also known as: |
Anti-Cathepsin C/DPP1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Cathepsin C/DPP1 |
| Specificity: |
This is a highly specific antibody against Cathepsin C/DPP1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DPP-I |
| Gene ID Number: |
1075 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, It is composed of a dimer of disulfide-linked heavy and light chains, Multiple transcript variants encoding different isoforms have been found for this gene, This enzyme requires chloride ions for activity and can degrade glucagon, [provided by RefSeq], a member of the peptidase C1 family, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme, both produced from a single protein precursor, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells, The protein encoded by this gene |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
DPP1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Cathepsin C/DPP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene: |
CTSC |
More about : CTSC |
| Gene target: |
Cathepsin C/DPP1 |
| Short name: |
Cathepsin C/DPP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Cathepsin C/DPP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2528 |
| Long gene name: |
cathepsin C |
| Synonyms gene: |
PLS PALS |
| Synonyms name: |
dipeptidyl peptidase 1 |
| Locus: |
11q14, 2 |
| Discovery year: |
1995-11-08 |
| GenBank acession: |
AK223038 |
| Entrez gene record: |
1075 |
| Pubmed identfication: |
7649281 9092576 |
| RefSeq identity: |
NM_001814 |
| Classification: |
Cathepsins |
| Havana BLAST/BLAT: |
OTTHUMG00000167290 |
| Locus Specific Databases: |
CTSCbase: Mutation registry for Papillon-Lefevre syndrome LRG_50 |