| Long name: |
Cathepsin C/DPP1 Primary Polyclonal Antibody |
| Also known as: |
Cathepsin C/DPP1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Cathepsin C/DPP1 |
| Specificity: |
This is a highly specific antibody against Cathepsin C/DPP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DPP-I |
| Gene ID number: |
1075 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, It is composed of a dimer of disulfide-linked heavy and light chains, Multiple transcript variants encoding different isoforms have been found for this gene, This enzyme requires chloride ions for activity and can degrade glucagon, [provided by RefSeq], a member of the peptidase C1 family, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme, both produced from a single protein precursor, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells, The protein encoded by this gene |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AI047818, CATC, CPPI, CTSC, Cathepsin C, Cathepsin J, DPP I, DPPI, Dipeptidyl peptidase 1, Dipeptidyl transferase, EC 3, HMS, JP, JPD, MGC126959, PALS, PLS, 1, 4, 14, Dipeptidyl peptidase I |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene: |
CTSC |
More about : CTSC |
| Gene target: |
Cathepsin C/DPP1 |
| Short name: |
Cathepsin C/DPP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cathepsin C/DPP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2528 |
| Long gene name: |
cathepsin C |
| Synonyms gene: |
PLS PALS |
| Synonyms: |
DPP1 |
| Synonyms name: |
dipeptidyl peptidase 1 |
| Locus: |
11q14, 2 |
| Discovery year: |
1995-11-08 |
| GenBank acession: |
AK223038 |
| Entrez gene record: |
1075 |
| Pubmed identfication: |
7649281 9092576 |
| RefSeq identity: |
NM_001814 |
| Classification: |
Cathepsins |
| Havana BLAST/BLAT: |
OTTHUMG00000167290 |
| Locus Specific Databases: |
CTSCbase: Mutation registry for Papillon-Lefevre syndrome LRG_50 |