| Long name: |
ALEXA FLUOR 488 Conjugated, Cathepsin D/CTSD Polyclonal Antibody |
| Also known as: |
Anti-Cathepsin D/CTSD PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Cathepsin D/CTSD |
| Specificity: |
This is a highly specific antibody against Cathepsin D/CTSD |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
115-141/412 |
| Subcellular location: |
Lysosome, Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Capsin D |
| Gene ID Number: |
1509 |
| Swiss Prot: |
P07339 |
| Tested applications: |
IF(ICC), IF(IHC-P) |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease, Acid protease active in intracellular protein breakdown |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CLN10 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Cathepsin D/CTSD Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene: |
CTSD |
More about : CTSD |
| Gene target: |
Cathepsin D/CTSD |
| Short name: |
Cathepsin D/CTSD Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Cathepsin D/cathepsin D (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CATD and IDBG-645332 and ENSBTAG00000007622 and 282883, CLN10 and CPSD and HEL-S-130P, CTSD and IDBG-19613 and ENSG00000117984 and 1509, Ctsd and IDBG-212523 and ENSMUSG00000007891 and 13033, Extracellular, protein binding, this GO :0004190 and aspartic-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005764 and lysosome and cellular component this GO :0006508 and proteolysis and biological process this GO :0008219 and cell death and biological process this GO :0019886 and antigen processing and presentation of exogenous peptide antigen via MHC class II and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0042470 and melanosome and cellular component this GO :0043202 and lysosomal lumen and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004190 : aspartic-type endopeptidase activity, this GO :0004190 : aspartic-type endopeptidase activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, cathepsin D |
| Identity: |
2529 |
| Long gene name: |
cathepsin D |
| Synonyms gene: |
CPSD |
| Synonyms gene name: |
cathepsin D (lysosomal aspartyl protease) |
| Synonyms name: |
ceroid-lipofuscinosis, neuronal 10 |
| Locus: |
11p15, 5 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M11233 |
| Entrez gene record: |
1509 |
| Pubmed identfication: |
3927292 |
| RefSeq identity: |
NM_001909 |
| Classification: |
Cathepsins |
| Havana BLAST/BLAT: |
OTTHUMG00000044760 |
| Locus Specific Databases: |
NCL Mutations , Neuronal Ceroid Lipofuscinoses |