| Long name: |
Biotin Conjugated, IL-17C Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IL-17C |
| Specificity: |
This is a highly specific antibody against IL-17C |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
90-130/197 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human IL-17C |
| Gene ID number: |
27189 |
| Swiss Prot: |
Q9P0M4 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts synergically with IL22 in inducing the expression of antibacterial peptides, Depending on the type of insult, Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases, REG3A and REG3G, S100A9, Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways, Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype, in an autocrine manner, including S100A8, including to intestinal bacterial pathogens, may have both protective and pathogenic properties, Cytokine that plays a crucial role in innate immunity of the epithelium |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
IL-17C CX2 IL-21 MGC126884 MGC138401 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IL-17C Conjugated |
| Short name: |
Conjugated, IL-17C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Interleukin-17C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5983 |
| Gene: |
IL17C |
More about : IL17C |
| Long gene name: |
interleukin 17C |
| Locus: |
16q24, 2 |
| Discovery year: |
2000-01-20 |
| GenBank acession: |
AF152099 |
| Entrez gene record: |
27189 |
| Pubmed identfication: |
10639155 |
| RefSeq identity: |
NM_013278 |
| Classification: |
Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000173241 |