| Long name: |
ALEXA FLUOR 488 Conjugated, IL-17C Polyclonal Antibody |
| Also known as: |
Anti-IL-17C PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IL-17C |
| Specificity: |
This is a highly specific antibody against IL-17C |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
90-130/197 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL-17C |
| Gene ID Number: |
27189 |
| Swiss Prot: |
Q9P0M4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts synergically with IL22 in inducing the expression of antibacterial peptides, Depending on the type of insult, Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases, REG3A and REG3G, S100A9, Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways, Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype, in an autocrine manner, including S100A8, including to intestinal bacterial pathogens, may have both protective and pathogenic properties, Cytokine that plays a crucial role in innate immunity of the epithelium |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
IL-17C CX2 IL-21 MGC126884 MGC138401 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the IL-17C Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
IL-17C |
| Short name: |
IL-17C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Interleukin-17C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5983 |
| Gene: |
IL17C |
More about : IL17C |
| Long gene name: |
interleukin 17C |
| Locus: |
16q24, 2 |
| Discovery year: |
2000-01-20 |
| GenBank acession: |
AF152099 |
| Entrez gene record: |
27189 |
| Pubmed identfication: |
10639155 |
| RefSeq identity: |
NM_013278 |
| Classification: |
Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000173241 |