| Long name: |
IL-17C Primary Polyclonal Antibody |
| Also known as: |
IL-17C PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
IL-17C |
| Specificity: |
This is a highly specific antibody against IL-17C |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
90-130/197 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL-17C |
| Gene ID number: |
27189 |
| Swiss Prot: |
Q9P0M4 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts synergically with IL22 in inducing the expression of antibacterial peptides, Depending on the type of insult, Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases, REG3A and REG3G, S100A9, Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways, Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype, in an autocrine manner, including S100A8, including to intestinal bacterial pathogens, may have both protective and pathogenic properties, Cytokine that plays a crucial role in innate immunity of the epithelium |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Cytokine CX2, IL-17C, IL17C, Interleukin-17C, UNQ561/PRO1122, CX2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IL-17C |
| Short name: |
IL-17C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Interleukin-17C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5983 |
| Gene: |
IL17C |
More about : IL17C |
| Long gene name: |
interleukin 17C |
| Synonyms: |
IL-17C CX2 IL-21 MGC126884 MGC138401 |
| Locus: |
16q24, 2 |
| Discovery year: |
2000-01-20 |
| GenBank acession: |
AF152099 |
| Entrez gene record: |
27189 |
| Pubmed identfication: |
10639155 |
| RefSeq identity: |
NM_013278 |
| Classification: |
Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000173241 |