Polycystin 2 Antibody, Cy7 Conjugated

Catalog number:	bs-2158R-Cy7 Buy Now
Price:	263 €
Supplier:	Bioss Primary Unconjugated Antibodies
Product name:	Polycystin 2 Antibody, Cy7 Conjugated
Quantity:	0.1ml
Related search:	antibody polycystin cilium pkd protein signaling

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Long name:	Cy7 Conjugated, Polycystin 2 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Cy7
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Polycystin 2
Specificity:	This antibody may have a minor secondary cross-reactivity towards Polycystin 2-like protein 1 due to a 71% non-contiguous sequence similarity in the immunogen sequence, This is a highly specific antibody against Polycystin 2
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	680-720/968
Subcellular location:	Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human Polycystin 2
Gene ID number:	5311
Swiss Prot:	Q13563
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Acts as a regulator of cilium length, Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity), PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis, The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling, Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040), leads to cilium shortening and thus decreases flow-induced signaling, together with PKD1, which decreases intracellular cAMP, Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	743nm/767nm
Synonyms:	APKD2, Autosomal dominant polycystic kidney disease type II protein, PKD2, PKD4, Pc-2, Polycystic kidney disease 2 protein, Polycystin-2, Polycystwin, R48321, TRPP2, Transient receptor potential cation channel subfamily P member 2, PC2
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated:	These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene target:	Polycystin 2 Conjugated
Short name:	Conjugated, Polycystin 2 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy7
Alternative name:	cyanine 7 coupled, Polycystin 2 (Antibody to)
Alternative technique:	antibodies

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• #polycystin
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• #protein
• #signaling