| Long name: |
Biotin Conjugated, Integrin Alpha V + Beta1 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Integrin Alpha V + Beta 1 |
| Specificity: |
This is a highly specific antibody against Integrin Alpha V + Beta 1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1-38/1048 |
| Subcellular location: |
Extracellular |
| Source: |
Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1 |
| Gene ID number: |
3685, 3688 |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands, In case of HIV-1 infection, Integrin alpha-V/beta-1 is a receptor for vitronectin, Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro), They recognize the sequence R-G-D in a wide array of ligands, cytotactin, fibrinogen, fibronectin, laminin, matrix metalloproteinase-2, osteomodulin, osteopontin, prothrombin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin and vWF, The alpha-V (ITGAV) integrins are receptors for vitronectin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CD29, CD51 Integrin beta-1: Fibronectin receptor subunit beta, GPIIA, Glycoprotein IIa, VLA-4 subunit beta, Vitronectin receptor subunit alpha, Integrin alpha-V: Integrin alpha-V |
| Description: |
Conjugated is a &alpha, - or alpha protein sometimes glycoprotein present in blood, The Integrin Alpha V + Beta1 Antibody |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Integrin Alpha V + Beta1 Conjugated |
| Short name: |
Conjugated, Integrin Alpha V + Beta1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Integrin a V and Beta1 (Antibody to) |
| Alternative technique: |
antibodies |