| Long name: |
FITC Conjugated, Integrin Alpha V + Beta1 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Integrin Alpha V + Beta 1 |
| Specificity: |
This is a highly specific antibody against Integrin Alpha V + Beta 1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1-38/1048 |
| Subcellular location: |
Extracellular |
| Source: |
Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1 |
| Gene ID number: |
3685, 3688 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands, In case of HIV-1 infection, Integrin alpha-V/beta-1 is a receptor for vitronectin, Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro), They recognize the sequence R-G-D in a wide array of ligands, cytotactin, fibrinogen, fibronectin, laminin, matrix metalloproteinase-2, osteomodulin, osteopontin, prothrombin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin and vWF, The alpha-V (ITGAV) integrins are receptors for vitronectin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CD29, CD51 Integrin beta-1: Fibronectin receptor subunit beta, GPIIA, Glycoprotein IIa, VLA-4 subunit beta, Vitronectin receptor subunit alpha, Integrin alpha-V: Integrin alpha-V |
| Description: |
FITC Conjugated is a &alpha, - or alpha protein sometimes glycoprotein present in blood, The Integrin Alpha V + Beta1 Antibody |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Integrin Alpha V + Beta1 Conjugated |
| Short name: |
FITC Conjugated, Integrin Alpha V + Beta1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Integrin a V and Beta1 (Antibody to) |
| Alternative technique: |
antibodies |