| Long name: |
Integrin Alpha V + Beta1 Antibody |
| Also known as: |
Integrin Alpha V + Beta1 Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Integrin Alpha V + Beta 1 |
| Specificity: |
This is a highly specific antibody against Integrin Alpha V + Beta 1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-38/1048 |
| Subcellular location: |
Extracellular |
| Source: |
Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1 |
| Gene ID number: |
3685, 3688 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands, In case of HIV-1 infection, Integrin alpha-V/beta-1 is a receptor for vitronectin, Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro), They recognize the sequence R-G-D in a wide array of ligands, cytotactin, fibrinogen, fibronectin, laminin, matrix metalloproteinase-2, osteomodulin, osteopontin, prothrombin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin and vWF, The alpha-V (ITGAV) integrins are receptors for vitronectin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD29, CD51 Integrin beta-1: Fibronectin receptor subunit beta, GPIIA, Glycoprotein IIa, VLA-4 subunit beta, Vitronectin receptor subunit alpha, Integrin alpha-V: Integrin alpha-V |
| Description: |
- or alpha protein sometimes glycoprotein present in blood, The Integrin Alpha V + Beta1 Antibody is a &alpha |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Integrin Alpha V + Beta1 |
| Short name: |
Integrin Alpha V + Beta1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Integrin a V and Beta1 (Antibody to) |
| Alternative technique: |
antibodies |