| Long name: |
HRP Conjugated, TRPV1/VR1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TRPV1/VR1 |
| Specificity: |
This is a highly specific antibody against TRPV1/VR1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
800-839/839 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human VR1 |
| Gene ID number: |
7442 |
| Swiss Prot: |
Q8NER1 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activation by vanilloids, Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects, Can be activated by endogenous compounds, Involved in mediation of inflammatory pain and hyperalgesia, Mild extracellular acidic pH (6, Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons, Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity), and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state, including 12-hydroperoxytetraenoic acid and bradykinin, like capsaicin, whereas acidic conditions (pH <, which involves PKC isozymes and PCL, 5) potentiates channel activation by noxious heat and vanilloids, 6) directly activate the channel, Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
TRPV1/VR1 Conjugated |
| Short name: |
Conjugated, TRPV1/VR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, TRPV1/VR1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12716 |
| Gene: |
TRPV1 |
More about : TRPV1 |
| Long gene name: |
transient receptor potential cation channel subfamily V member 1 |
| Synonyms gene: |
VR1 |
| Synonyms gene name: |
member 1 , subfamily V, vanilloid receptor subtype 1 transient receptor potential cation channel |
| Locus: |
17p13, 2 |
| Discovery year: |
1997-12-05 |
| GenBank acession: |
AJ272063 |
| Entrez gene record: |
7442 |
| Pubmed identfication: |
9349813 11549313 16382100 |
| RefSeq identity: |
NM_018727 |
| Classification: |
Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000177649 |