TRPV1/VR1 Antibody, ALEXA FLUOR 488

Contact us
Catalog number: bs-1931R-A488
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: TRPV1/VR1 Antibody, ALEXA FLUOR 488
Quantity: 100ul
Related search:

More details :

Long name: ALEXA FLUOR 488 Conjugated, TRPV1/VR1 Polyclonal Antibody
Also known as: Anti-TRPV1/VR1 PAb ALEXA FLUOR 488
Category: Conjugated Primary Antibodies
Conjugated with: 488, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: TRPV1/VR1
Specificity: This is a highly specific antibody against TRPV1/VR1
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 800-839/839
Subcellular location: Cytoplasm
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human VR1
Gene ID Number: 7442
Swiss Prot: Q8NER1
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Activation by vanilloids, Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects, Can be activated by endogenous compounds, Involved in mediation of inflammatory pain and hyperalgesia, Mild extracellular acidic pH (6, Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons, Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity), and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state, including 12-hydroperoxytetraenoic acid and bradykinin, like capsaicin, whereas acidic conditions (pH <, which involves PKC isozymes and PCL, 5) potentiates channel activation by noxious heat and vanilloids, 6) directly activate the channel, Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 499nm/519nm
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TRPV1/VR1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: TRPV1/VR1
Short name: TRPV1/VR1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 488
Alternative name: ALEXA FLUOR 488, TRPV1/VR1 (Antibody to)
Alternative technique: antibodies
Identity: 12716
Gene: TRPV1 | More about : TRPV1
Long gene name: transient receptor potential cation channel subfamily V member 1
Synonyms gene: VR1
Synonyms gene name: member 1 , subfamily V, vanilloid receptor subtype 1 transient receptor potential cation channel
Locus: 17p13, 2
Discovery year: 1997-12-05
GenBank acession: AJ272063
Entrez gene record: 7442
Pubmed identfication: 9349813 11549313 16382100
RefSeq identity: NM_018727
Classification: Ankyrin repeat domain containing Transient receptor potential cation channels
Havana BLAST/BLAT: OTTHUMG00000177649

Related Products :