TRPV1/VR1 Antibody

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Catalog number: bs-1931R
Price: 263 €
Supplier: Bioss Primary Unconjugated Antibodies
Product name: TRPV1/VR1 Antibody
Quantity: 0.1ml
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Long name: TRPV1/VR1 Primary Polyclonal Antibody
Also known as: TRPV1/VR1 PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: TRPV1/VR1
Specificity: This is a highly specific antibody against TRPV1/VR1
Modification(s): None
Modification site(s): Unmodified antibody
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 800-839/839
Subcellular location: Cytoplasm
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human VR1
Gene ID number: 7442
Swiss Prot: Q8NER1
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: Activation by vanilloids, Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects, Can be activated by endogenous compounds, Involved in mediation of inflammatory pain and hyperalgesia, Mild extracellular acidic pH (6, Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons, Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity), and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state, including 12-hydroperoxytetraenoic acid and bradykinin, like capsaicin, whereas acidic conditions (pH <, which involves PKC isozymes and PCL, 5) potentiates channel activation by noxious heat and vanilloids, 6) directly activate the channel, Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: Capsaicin receptor, OTRPC1, Osm-9-like TRP channel 1, Transient receptor potential cation channel subfamily V member 1, TrpV1, Vanilloid receptor 1, VR1
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: TRPV1/VR1
Short name: TRPV1/VR1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: TRPV1/VR1 (Antibody to)
Alternative technique: antibodies
Identity: 12716
Gene: TRPV1 | More about : TRPV1
Long gene name: transient receptor potential cation channel subfamily V member 1
Synonyms gene: VR1
Synonyms gene name: member 1 , subfamily V, vanilloid receptor subtype 1 transient receptor potential cation channel
Locus: 17p13, 2
Discovery year: 1997-12-05
GenBank acession: AJ272063
Entrez gene record: 7442
Pubmed identfication: 9349813 11549313 16382100
RefSeq identity: NM_018727
Classification: Ankyrin repeat domain containing Transient receptor potential cation channels
Havana BLAST/BLAT: OTTHUMG00000177649

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