| Long name: |
ALEXA FLUOR 488 Conjugated, PEA3 Polyclonal Antibody |
| Also known as: |
Anti-PEA3 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PEA3 |
| Specificity: |
This is a highly specific antibody against PEA3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PEA3 |
| Gene ID Number: |
2118 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Drosophila E74, Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element, Ets-2 and Fli-1, For instance, It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core, PEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells, These include mouse PU, This is in contrast to other members of the Ets gene family, although PU, but does not bind to the sequence 5'-AGGAAC-3', chicken and human Ets-2 and rat GABP-a, each of which is expressed primarily in cells of hematopoietic origin, mouse and human Ets-1, recognized by PU, such as Ets-1, 1, 1, 1 binds equally well to both sequences, Several members of the Ets gene family are known to encode sequence-specific DNA binding proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
E1A-F E1AF PEA3 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PEA3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
PEA3 |
| Short name: |
PEA3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, PEA3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3493 |
| Gene: |
ETV4 |
More about : ETV4 |
| Long gene name: |
ETS variant 4 |
| Synonyms gene name: |
E1AF) , ets variant gene 4 (E1A enhancer-binding protein |
| Synonyms name: |
E1A enhancer binding protein |
| Locus: |
17q21, 31 |
| Discovery year: |
1995-03-27 |
| GenBank acession: |
U18018 |
| Entrez gene record: |
2118 |
| Pubmed identfication: |
8530053 1547944 |
| RefSeq identity: |
NM_001986 |
| Classification: |
ETS transcription factor family |
| Havana BLAST/BLAT: |
OTTHUMG00000180884 |