| Catalog number: | bs-1790R-A488 |
|---|---|
| Price: | 456 € |
| Supplier: | fabgen |
| Product name: | CRMP2/TOAD64 Antibody, ALEXA FLUOR 488 |
| Quantity: | 100 µg |
| Related search: |
| Long name: | ALEXA FLUOR 488 Conjugated, CRMP2/TOAD64 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-CRMP2/TOAD64 PAb ALEXA FLUOR 488 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 488, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | CRMP2/TOAD64 |
| Specificity: | This is a highly specific antibody against CRMP2/TOAD64 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CRMP2 |
| Gene ID Number: | 1808 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly, CRMP2 is upregulated after axotomy, CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification, CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome, CRMPs localize to the lamellipodia and filopodia of axonal growth cones, Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease, Interaction studies have implicated phospholipase D2 (PLD2), Moreover, The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction, and appears to increase the formation of axon-type processes from hippocampal neurons, and intersectin in CRMP function, suggesting a role in axon guidance, the cytosolic tyrosine kinase Fes, Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 499nm/519nm |
| Synonyms: | DRP-2 DHPRP2 CRMP2 DRP2 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CRMP2/TOAD64 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | CRMP2/TOAD64 |
| Short name: | CRMP2/TOAD64 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 488 |
| Alternative name: | ALEXA FLUOR 488, CRMP2/TOAD64 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 3014 |
| Gene: | DPYSL2 | More about : DPYSL2 |
| Long gene name: | dihydropyrimidinase like 2 |
| Synonyms gene name: | dihydropyrimidinase-like 2 |
| Locus: | 8p21, 2 |
| Discovery year: | 1997-02-27 |
| GenBank acession: | D78013 |
| Entrez gene record: | 1808 |
| Pubmed identfication: | 8973361 |
| RefSeq identity: | NM_001386 |
| Havana BLAST/BLAT: | OTTHUMG00000099439 |
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