| Long name: |
CRMP2/TOAD64 Primary Polyclonal Antibody |
| Also known as: |
CRMP2/TOAD64 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CRMP2/TOAD64 |
| Specificity: |
This is a highly specific antibody against CRMP2/TOAD64 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CRMP2 |
| Gene ID number: |
1808 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly, CRMP2 is upregulated after axotomy, CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification, CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome, CRMPs localize to the lamellipodia and filopodia of axonal growth cones, Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease, Interaction studies have implicated phospholipase D2 (PLD2), Moreover, The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction, and appears to increase the formation of axon-type processes from hippocampal neurons, and intersectin in CRMP function, suggesting a role in axon guidance, the cytosolic tyrosine kinase Fes, Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CRAM, CRMP 2, CRMP-2, CRMP2, Collapsin response mediator protein hCRMP 2, DHPRP 2, DHPRP2, DPYL 2, DPYL2, DPYL2_HUMAN, DPYSL 2, DRP 2, DRP-2, DRP2, Dihydr pyrimidinase 2, Dihydropyrimidinase 2, Dihydropyrimidinase like 2, Dihydropyrimidinase like 2 long form, Dihydropyrimidinase related protein 2, Dihydropyrimidinase-related protein 2, Dpysl2, Musunc 33, Musunc33, N2A3, TOAD 64, TOAD64, ULIP 2 protein, ULIP-2, Ulip2, Unc-33-like phosphoprotein 2, Collapsin response mediator protein 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CRMP2/TOAD64 |
| Short name: |
CRMP2/TOAD64 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CRMP2/TOAD64 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3014 |
| Gene: |
DPYSL2 |
More about : DPYSL2 |
| Long gene name: |
dihydropyrimidinase like 2 |
| Synonyms gene name: |
dihydropyrimidinase-like 2 |
| Synonyms: |
DRP-2 DHPRP2 CRMP2 DRP2 |
| Locus: |
8p21, 2 |
| Discovery year: |
1997-02-27 |
| GenBank acession: |
D78013 |
| Entrez gene record: |
1808 |
| Pubmed identfication: |
8973361 |
| RefSeq identity: |
NM_001386 |
| Havana BLAST/BLAT: |
OTTHUMG00000099439 |