| Long name: |
FITC Conjugated, FDC-SP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FDC-SP |
| Specificity: |
This is a highly specific antibody against FDC-SP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
5-50/85 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from rat FDC-SP |
| Gene ID number: |
494224 |
| Swiss Prot: |
Q5R1M6 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
B cells form germinal centers around follicular dendritic cells in lymphoid organs, Dendritic cells form from monocytes, Evidence in pathological tissue and functional studies suggests it binds to an epitope expressed by antigen presenting cells, It is purely a resident of the follicles of secondary lymphoid organs, The monocytes in turn are formed from stem cells in the bone marrow, This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell, Within the macrophage/dendritic cell populations the epitope seen by RFD1 is coexpressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation, can turn into dendritic cells or macrophages, depending on the right signal, white blood cells which circulate in the body and, Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles, In normal tissue this antibody identifies dendritic cells and a proportion of B lymphocytes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FDC-SP |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FDC-SP Conjugated |
| Short name: |
FITC Conjugated, FDC-SP Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, FDC-SP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19215 |
| Gene: |
FDCSP |
More about : FDCSP |
| Long gene name: |
follicular dendritic cell secreted protein |
| Synonyms gene: |
C4orf7 |
| Synonyms gene name: |
chromosome 4 open reading frame 7 |
| Locus: |
4q13, 3 |
| Discovery year: |
2002-09-17 |
| GenBank acession: |
AF435080 |
| Entrez gene record: |
260436 |
| Pubmed identfication: |
12193705 17548624 20811673 |
| RefSeq identity: |
NM_152997 |
| Havana BLAST/BLAT: |
OTTHUMG00000129393 |