| Long name: |
FDC-SP Primary Polyclonal Antibody |
| Also known as: |
FDC-SP PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FDC-SP |
| Specificity: |
This is a highly specific antibody against FDC-SP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
5-50/85 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from rat FDC-SP |
| Gene ID number: |
494224 |
| Swiss Prot: |
Q5R1M6 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
B cells form germinal centers around follicular dendritic cells in lymphoid organs, Dendritic cells form from monocytes, Evidence in pathological tissue and functional studies suggests it binds to an epitope expressed by antigen presenting cells, It is purely a resident of the follicles of secondary lymphoid organs, The monocytes in turn are formed from stem cells in the bone marrow, This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell, Within the macrophage/dendritic cell populations the epitope seen by RFD1 is coexpressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation, can turn into dendritic cells or macrophages, depending on the right signal, white blood cells which circulate in the body and, Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles, In normal tissue this antibody identifies dendritic cells and a proportion of B lymphocytes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FDC secreted protein, FDCs, Follicular dendritic cell, Follicular dendritic cell, Follicular dendritic cell secreted peptide, Follicular dendritic cell secreted protein, FDC |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FDC-SP |
| Short name: |
FDC-SP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FDC-SP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19215 |
| Gene: |
FDCSP |
More about : FDCSP |
| Long gene name: |
follicular dendritic cell secreted protein |
| Synonyms gene: |
C4orf7 |
| Synonyms gene name: |
chromosome 4 open reading frame 7 |
| Synonyms: |
FDC-SP |
| Locus: |
4q13, 3 |
| Discovery year: |
2002-09-17 |
| GenBank acession: |
AF435080 |
| Entrez gene record: |
260436 |
| Pubmed identfication: |
12193705 17548624 20811673 |
| RefSeq identity: |
NM_152997 |
| Havana BLAST/BLAT: |
OTTHUMG00000129393 |