| Long name: |
ALEXA FLUOR 488 Conjugated, FDC-SP Polyclonal Antibody |
| Also known as: |
Anti-FDC-SP PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FDC-SP |
| Specificity: |
This is a highly specific antibody against FDC-SP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
5-50/85 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from rat FDC-SP |
| Gene ID Number: |
494224 |
| Swiss Prot: |
Q5R1M6 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
B cells form germinal centers around follicular dendritic cells in lymphoid organs, Dendritic cells form from monocytes, Evidence in pathological tissue and functional studies suggests it binds to an epitope expressed by antigen presenting cells, It is purely a resident of the follicles of secondary lymphoid organs, The monocytes in turn are formed from stem cells in the bone marrow, This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell, Within the macrophage/dendritic cell populations the epitope seen by RFD1 is coexpressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation, can turn into dendritic cells or macrophages, depending on the right signal, white blood cells which circulate in the body and, Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles, In normal tissue this antibody identifies dendritic cells and a proportion of B lymphocytes |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
FDC-SP |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FDC-SP Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
FDC-SP |
| Short name: |
FDC-SP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, FDC-SP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19215 |
| Gene: |
FDCSP |
More about : FDCSP |
| Long gene name: |
follicular dendritic cell secreted protein |
| Synonyms gene: |
C4orf7 |
| Synonyms gene name: |
chromosome 4 open reading frame 7 |
| Locus: |
4q13, 3 |
| Discovery year: |
2002-09-17 |
| GenBank acession: |
AF435080 |
| Entrez gene record: |
260436 |
| Pubmed identfication: |
12193705 17548624 20811673 |
| RefSeq identity: |
NM_152997 |
| Havana BLAST/BLAT: |
OTTHUMG00000129393 |