| Long name: |
Biotin Conjugated, MASP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MASP |
| Specificity: |
This is a highly specific antibody against MASP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
130-180/488 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human MASP |
| Gene ID number: |
5648 |
| Swiss Prot: |
P48740 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction, Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5, The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them, Functions in the lectin pathway of complement |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
MASP |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MASP Conjugated |
| Short name: |
Conjugated, MASP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, MASP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6901 |
| Gene: |
MASP1 |
More about : MASP1 |
| Long gene name: |
mannan binding lectin serine peptidase 1 |
| Synonyms gene: |
CRARF PRSS5 |
| Synonyms gene name: |
mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| Synonyms name: |
C4/C2 activating component of Ra-reactive factor |
| Locus: |
3q27, 3 |
| Discovery year: |
1995-07-06 |
| GenBank acession: |
D28593 |
| Entrez gene record: |
5648 |
| Pubmed identfication: |
8018603 8240317 |
| RefSeq identity: |
NM_001879 |
| Classification: |
Sushi domain containing Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000156461 |
| Locus Specific Databases: |
LRG_349 |