| Long name: |
ALEXA FLUOR 647 Conjugated, MASP Polyclonal Antibody |
| Also known as: |
Anti-MASP PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MASP |
| Specificity: |
This is a highly specific antibody against MASP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
130-180/488 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MASP |
| Gene ID Number: |
5648 |
| Swiss Prot: |
P48740 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction, Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5, The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them, Functions in the lectin pathway of complement |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MASP |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MASP Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
MASP |
| Short name: |
MASP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, MASP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6901 |
| Gene: |
MASP1 |
More about : MASP1 |
| Long gene name: |
mannan binding lectin serine peptidase 1 |
| Synonyms gene: |
CRARF PRSS5 |
| Synonyms gene name: |
mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| Synonyms name: |
C4/C2 activating component of Ra-reactive factor |
| Locus: |
3q27, 3 |
| Discovery year: |
1995-07-06 |
| GenBank acession: |
D28593 |
| Entrez gene record: |
5648 |
| Pubmed identfication: |
8018603 8240317 |
| RefSeq identity: |
NM_001879 |
| Classification: |
Sushi domain containing Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000156461 |
| Locus Specific Databases: |
LRG_349 |