| Long name: |
MASP Primary Polyclonal Antibody |
| Also known as: |
MASP PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MASP |
| Specificity: |
This is a highly specific antibody against MASP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
130-180/488 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MASP |
| Gene ID number: |
5648 |
| Swiss Prot: |
P48740 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction, Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5, The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them, Functions in the lectin pathway of complement |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CRARF, CRARF1, Complement factor MASP-3, Complement-activating component of Ra-reactive factor, MAP1, MASP, MASP-1, MASP1, MASP3, MAp44, Mannan-binding lectin serine protease 1, Mannose-binding lectin-associated serine protease 1, Mannose-binding protein-associated serine protease, PRSS5, Ra-reactive factor serine protease p100, RaRF, Serine protease 5, 3MC1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MASP |
| Short name: |
MASP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MASP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6901 |
| Gene: |
MASP1 |
More about : MASP1 |
| Long gene name: |
mannan binding lectin serine peptidase 1 |
| Synonyms gene: |
CRARF PRSS5 |
| Synonyms gene name: |
mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| Synonyms: |
MASP |
| Synonyms name: |
C4/C2 activating component of Ra-reactive factor |
| Locus: |
3q27, 3 |
| Discovery year: |
1995-07-06 |
| GenBank acession: |
D28593 |
| Entrez gene record: |
5648 |
| Pubmed identfication: |
8018603 8240317 |
| RefSeq identity: |
NM_001879 |
| Classification: |
Sushi domain containing Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000156461 |
| Locus Specific Databases: |
LRG_349 |