| Catalog number: | bs-13702R-Biotin |
|---|---|
| Price: | 637 € |
| Supplier: | genways |
| Product name: | SKAP55 Antibody, Biotin Conjugated |
| Quantity: | 1 vial |
| Related search: |
| Long name: | Biotin Conjugated, SKAP55 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Biotinylated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | SKAP55 |
| Specificity: | This is a highly specific antibody against SKAP55 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human SKAP55 |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: | Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells, SKAP55 associates with SLAP-130, SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines, SKAP55-R, The human SKAP55 gene maps to chromosome 17q21, another component of the Fyn complex, contains a coiled-coil N-terminal domain, similar in overall structure to SKAP55, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation, 32 and encodes a 359 amino acid protein, Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: | SKAP55 |
| Properties: | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | SKAP55 Conjugated |
| Short name: | Conjugated, SKAP55 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Biotin |
| Alternative name: | biotinilated coupled, SKAP55 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 15605 |
| Gene: | SKAP1 | More about : SKAP1 |
| Long gene name: | src kinase associated phosphoprotein 1 |
| Synonyms gene: | SCAP1 |
| Synonyms gene name: | src family associated phosphoprotein 1 |
| Locus: | 17q21, 32 |
| Discovery year: | 2001-06-21 |
| GenBank acession: | Y11215 |
| Entrez gene record: | 8631 |
| Pubmed identfication: | 9195899 |
| RefSeq identity: | NM_003726 |
| Classification: | Pleckstrin homology domain containing |
| Havana BLAST/BLAT: | OTTHUMG00000178823 |
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