| Long name: |
SKAP55 Primary Polyclonal Antibody |
| Also known as: |
SKAP55 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SKAP55 |
| Specificity: |
This is a highly specific antibody against SKAP55 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SKAP55 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells, SKAP55 associates with SLAP-130, SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines, SKAP55-R, The human SKAP55 gene maps to chromosome 17q21, another component of the Fyn complex, contains a coiled-coil N-terminal domain, similar in overall structure to SKAP55, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation, 32 and encodes a 359 amino acid protein, Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
SCAP 1, SCAP1, SKAP 1, SKAP 55, SKAP-55, SKAP1_HUMAN, SKAP55 adaptor protein, SRC family associated phosphoprotein 1, SRC kinase associated phosphoprotein 55 kD, Skap1, Src family-associated phosphoprotein 1, Src kinase associated phosphoprotein 1, Src kinase associated phosphoprotein of 55 kDa, Src kinase-associated phosphoprotein 1, Src kinase-associated phosphoprotein of 55 kDa, pp55 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SKAP55 |
| Short name: |
SKAP55 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SKAP55 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15605 |
| Gene: |
SKAP1 |
More about : SKAP1 |
| Long gene name: |
src kinase associated phosphoprotein 1 |
| Synonyms gene: |
SCAP1 |
| Synonyms gene name: |
src family associated phosphoprotein 1 |
| Synonyms: |
SKAP55 |
| Locus: |
17q21, 32 |
| Discovery year: |
2001-06-21 |
| GenBank acession: |
Y11215 |
| Entrez gene record: |
8631 |
| Pubmed identfication: |
9195899 |
| RefSeq identity: |
NM_003726 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000178823 |