| Alternative name 1: |
Clone: YGL 386, PE, Rat Mab anti-Mouse, GITR Ligand (GITR-L) |
| Alternative name 2: |
Clone: YGL 386, PE, Rat Mab antibody-Mouse, GITR Ligand (GITR-L) |
| Alternative name 3: |
Clone: YGL 386, PE, Rattus norvegicus Mab antibody-Mus musculus, GITR Ligand (GITR-L) |
| Alternative name 4: |
anti-GITR Ligand GITR-L Clone: YGL 386 |
| Alternative name 5: |
GITR Ligand GITR-L Clone: YGL 386 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Rattus norvegicus, Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal PE, GITR Ligand (GITR-L) YGL 386 |
| Short name: |
Mouse Monoclonal antibody-Mouse, PE, GITR Ligand (GITR-L) Clone: YGL 386 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Host: |
Rat |
| Label: |
PE |
| Species: |
Mouses, Rats, Mouse |
| Alternative name: |
Rat Mouse monoclonal (Antibody to)-Mouse, clonality: YGL 386, peroxidase, GITR Ligand (GITR-L) |
| Alternative technique: |
murine |
| Identity: |
11914 |
| Gene: |
TNFRSF18 |
More about : TNFRSF18 |
| Long gene name: |
TNF receptor superfamily member 18 |
| Synonyms gene name: |
member 18 , tumor necrosis factor receptor superfamily |
| Synonyms: |
AITR GITR CD357 |
| Locus: |
1p36, 33 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
AF125304 |
| Entrez gene record: |
8784 |
| Pubmed identfication: |
9177197 10037686 |
| RefSeq identity: |
NM_004195 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000001414 |