| Also known as: |
TNFRSF18 / GITR |
| Other names: |
Activation-inducible TNFR family receptor, CD_antigen: CD357, Glucocorticoid-induced TNFR-related protein, TNF receptor superfamily activation-inducible protein, Tumor necrosis factor receptor superfamily member 18, activation-inducible TNFR family receptor, glucocorticoid-induced TNFR-related protein, member 18, tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 18, tumor necrosis factor receptor superfamily member 18 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TNFRSF18 |
| Gene name synonims: |
GITR |
| Other gene names: |
AITR, AITR, CD357, GITR, GITR, GITR-D, TNFRSF18, TNFRSF18 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b, k |
| Clone: |
2H4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human TNFRSF18 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Aliquot to avoid repeated freezing and thawing, or lower, Store the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2H4] (IgG2b, k) TNFRSF18 / GITR |
| Short name: |
Mouse Monoclonal [clone 2H4] (IgG2b, k) TNFRSF18 / GITR Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
member 18 / GITR (Antibody to), sapiens tumor necrosis factor receptor superfamily, Mouse monoclonal [clonality 2H4] (IgG2b, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AITR and CD357 and GITR and GITR-D, Extracellular, TNFRSF18 and IDBG-635325 and ENSBTAG00000015632 and 516256, TNFRSF18 and IDBG-84584 and ENSG00000186891 and 8784, Tnfrsf18 and IDBG-208288 and ENSMUSG00000041954 and 21936, member 18, protein binding, this GO :0005031 and tumor necrosis factor-activated receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process, this GO :0005031 : tumor necrosis factor-activated receptor activity, this GO :0005031 : tumor necrosis factor-activated receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, tumor necrosis factor receptor superfamily |
| Identity: |
11914 |
| Gene: |
TNFRSF18 |
More about : TNFRSF18 |
| Long gene name: |
TNF receptor superfamily member 18 |
| Synonyms gene name: |
member 18 , tumor necrosis factor receptor superfamily |
| Synonyms: |
AITR GITR CD357 |
| Locus: |
1p36, 33 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
AF125304 |
| Entrez gene record: |
8784 |
| Pubmed identfication: |
9177197 10037686 |
| RefSeq identity: |
NM_004195 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000001414 |