| Alternative name 1: |
(CCR7), ALEXA 647 conj, Clone: 4B12, Rat Mab anti-Mouse, flow, CD197 |
| Alternative name 2: |
(CCR7), ALEXA 647 conj, Clone: 4B12, Rat Mab antibody-Mouse, flow, CD197 |
| Alternative name 3: |
(CCR7), ALEXA 647 conj, Clone: 4B12, Rattus norvegicus Mab antibody-Mus musculus, flow, CD197 |
| Alternative name 4: |
anti-CD197 CCR7 Clone: 4B12 flow ALEXA 647 |
| Alternative name 5: |
CD197 CCR7 Clone: 4B12 flow ALEXA 647 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Rattus norvegicus, Mus musculus |
| French translation: |
anticorps |
| Gene target: |
(CCR7) 4B12, 647 conj, Monoclonal , CD197 |
| Short name: |
(CCR7) Clone: 4B12, 647 conj, Mouse Monoclonal antibody-Mouse, CD197 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Host: |
Rat |
| Label: |
ALEXA |
| Species: |
Mouses, Rats, Mouse |
| Alternative name: |
(chemokine (C-C motif) receptor 7), ALEXA 647 conj, Rat Mouse monoclonal (Antibody to)-Mouse, clonality: 4B12, flow, CD197 |
| Alternative technique: |
murine |
| Alternative to gene target: |
BLR2 and CC-CKR-7 and CCR-7 and CD197 and CDw197 and CMKBR7 and EBI1, C-C motif chemokine 21 receptor activity, CCR7 and IDBG-47801 and ENSG00000126353 and 1236, CCR7 and IDBG-639725 and ENSBTAG00000015133 and 510668, Ccr7 and IDBG-210918 and ENSMUSG00000037944 and 12775, Cell surfaces, this GO :0001768 and establishment of T cell polarity and biological process this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002408 and myeloid dendritic cell chemotaxis and biological process this GO :0002606 and positive regulation of dendritic cell antigen processing and presentation and biological process this GO :0002885 and positive regulation of hypersensitivity and biological process this GO :0002922 and positive regulation of humoral immune response and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0031274 and positive regulation of pseudopodium assembly and biological process this GO :0031529 and ruffle organization and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032649 and regulation of interferon-gamma production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032862 and activation of Rho GTPase activity and biological process this GO :0034695 and response to prostaglandin E and biological process this GO :0035757 and chemokine (C-C motif) ligand 19 binding and molecular function this GO :0035758 and chemokine (C-C motif) ligand 21 binding and molecular function this GO :0038115 and chemokine (C-C motif) ligand 19 signaling pathway and biological process this GO :0038116 and chemokine (C-C motif) ligand 21 signaling pathway and biological process this GO :0038117 and C-C motif chemokine 19 receptor activity and molecular function this GO :0038121 and C-C motif chemokine 21 receptor activity and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0045087 and innate immune response and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0050706 and regulation of interleukin-1 beta secretion and biological process this GO :0050862 and positive regulation of T cell receptor signaling pathway and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0051491 and positive regulation of filopodium assembly and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process this GO :0071731 and response to nitric oxide and biological process this GO :0072610 and interleukin-12 secretion and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process this GO :0097022 and lymphocyte migration into lymph node and biological process this GO :0097029 and mature dendritic cell differentiation and biological process this GO :2000107 and negative regulation of leukocyte apoptotic process and biological process this GO :2000147 and positive regulation of cell motility and biological process this GO :2000510 and positive regulation of dendritic cell chemotaxis and biological process this GO :2000522 and positive regulation of immunological synapse formation and biological process this GO :2000525 and positive regulation of T cell costimulation and biological process this GO :2000526 and positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation and biological process this GO :2000547 and regulation of dendritic cell dendrite assembly and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0005515 : protein binding and also this GO :0016493 : C-C chemokine receptor activity and also this GO :0035757 : chemokine (C-C motif) ligand 19 binding and also this GO :0035758 : chemokine (C-C motif) ligand 21 binding and also this GO :0038117 : C-C motif chemokine 19 receptor activity and also this GO :0038121 : C-C motif chemokine 21 receptor activity, this GO :0005515 : protein binding, this GO :0016493 : C-C chemokine receptor activity, this GO :0035757 : chemokine (C-C motif) ligand 19 binding, this GO :0035758 : chemokine (C-C motif) ligand 21 binding, this GO :0038117 : C-C motif chemokine 19 receptor activity, this GO :0038121 : C-C motif chemokine 21 receptor activity, chemokine (C-C motif) receptor 7 |
| Identity: |
1608 |
| Gene: |
CCR7 |
More about : CCR7 |
| Long gene name: |
C-C motif chemokine receptor 7 |
| Synonyms gene: |
CMKBR7 EBI1 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 7 |
| Synonyms: |
BLR2 CDw197 CD197 |
| Locus: |
17q21, 2 |
| Discovery year: |
1994-05-17 |
| Entrez gene record: |
1236 |
| Pubmed identfication: |
8383238 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133375 |