| Long name: |
ALEXA FLUOR 488 Conjugated, CCR7/CD197 Polyclonal Antibody |
| Also known as: |
Anti-CCR7/CD197 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCR7/CD197 |
| Specificity: |
This is a highly specific antibody against CCR7/CD197 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
25-59/379 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from mouse CCR7 |
| Gene ID Number: |
12775 |
| Swiss Prot: |
P47774 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CCR7 has been reported to be expressed in blood, ESTs have been isolated from blood, It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor, This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and intestine, and is thought to be a mediator of EBV effects on B lymphocytes, and thymus libraries, as well as stimulate dendritic cell maturation, bone marrow, embryo, lymph node, lymph node, CCR7 is a member of the G protein coupled receptor family (subfamily : chemokine) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
BLR2 CDw197 CD197 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CCR7/CD197 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CCR7/CD197 |
| Short name: |
CCR7/CD197 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, chemokine (C-C motif) receptor 7/CD197 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BLR2 and CC-CKR-7 and CCR-7 and CD197 and CDw197 and CMKBR7 and EBI1, C-C motif chemokine 21 receptor activity, CCR7 and IDBG-47801 and ENSG00000126353 and 1236, CCR7 and IDBG-639725 and ENSBTAG00000015133 and 510668, Ccr7 and IDBG-210918 and ENSMUSG00000037944 and 12775, Cell surfaces, this GO :0001768 and establishment of T cell polarity and biological process this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002408 and myeloid dendritic cell chemotaxis and biological process this GO :0002606 and positive regulation of dendritic cell antigen processing and presentation and biological process this GO :0002885 and positive regulation of hypersensitivity and biological process this GO :0002922 and positive regulation of humoral immune response and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0031274 and positive regulation of pseudopodium assembly and biological process this GO :0031529 and ruffle organization and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032649 and regulation of interferon-gamma production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032862 and activation of Rho GTPase activity and biological process this GO :0034695 and response to prostaglandin E and biological process this GO :0035757 and chemokine (C-C motif) ligand 19 binding and molecular function this GO :0035758 and chemokine (C-C motif) ligand 21 binding and molecular function this GO :0038115 and chemokine (C-C motif) ligand 19 signaling pathway and biological process this GO :0038116 and chemokine (C-C motif) ligand 21 signaling pathway and biological process this GO :0038117 and C-C motif chemokine 19 receptor activity and molecular function this GO :0038121 and C-C motif chemokine 21 receptor activity and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0045087 and innate immune response and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0050706 and regulation of interleukin-1 beta secretion and biological process this GO :0050862 and positive regulation of T cell receptor signaling pathway and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0051491 and positive regulation of filopodium assembly and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process this GO :0071731 and response to nitric oxide and biological process this GO :0072610 and interleukin-12 secretion and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process this GO :0097022 and lymphocyte migration into lymph node and biological process this GO :0097029 and mature dendritic cell differentiation and biological process this GO :2000107 and negative regulation of leukocyte apoptotic process and biological process this GO :2000147 and positive regulation of cell motility and biological process this GO :2000510 and positive regulation of dendritic cell chemotaxis and biological process this GO :2000522 and positive regulation of immunological synapse formation and biological process this GO :2000525 and positive regulation of T cell costimulation and biological process this GO :2000526 and positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation and biological process this GO :2000547 and regulation of dendritic cell dendrite assembly and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0005515 : protein binding and also this GO :0016493 : C-C chemokine receptor activity and also this GO :0035757 : chemokine (C-C motif) ligand 19 binding and also this GO :0035758 : chemokine (C-C motif) ligand 21 binding and also this GO :0038117 : C-C motif chemokine 19 receptor activity and also this GO :0038121 : C-C motif chemokine 21 receptor activity, this GO :0005515 : protein binding, this GO :0016493 : C-C chemokine receptor activity, this GO :0035757 : chemokine (C-C motif) ligand 19 binding, this GO :0035758 : chemokine (C-C motif) ligand 21 binding, this GO :0038117 : C-C motif chemokine 19 receptor activity, this GO :0038121 : C-C motif chemokine 21 receptor activity, chemokine (C-C motif) receptor 7 |
| Identity: |
1608 |
| Gene: |
CCR7 |
More about : CCR7 |
| Long gene name: |
C-C motif chemokine receptor 7 |
| Synonyms gene: |
CMKBR7 EBI1 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 7 |
| Locus: |
17q21, 2 |
| Discovery year: |
1994-05-17 |
| Entrez gene record: |
1236 |
| Pubmed identfication: |
8383238 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133375 |