| Long name: |
FITC Conjugated, NSP3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NSP3 |
| Specificity: |
This is a highly specific antibody against NSP3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NSP3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
FAN (for factor associated with neutral sphingomyelinase (N-SMase) activation) is an intermediate protein that interacts with TNF-R1 to initiate TNF signaling events, FAN binds to TNF-R1 at the cytoplasmic NSD (N-SMase activating domain), FAN contains four carboxy-terminal WD-repeat domains which appear to be involved in protein-protein interaction, N-SMase has been shown to be involved in TNF-induced Raf-1 activation (6), The FAN WD-repeats may mediate the interaction between FAN and TNF-R1 (5), The majority of TNF functions are primarily mediated through TNF-R1 (1, These receptors, are expressed on most cell types (1, designated TNF-R1 and TNF-R2, which results in the initiation of the N-SMase pathway (5), 2), 3), 4), Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated through two distinct cell surface receptors (1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
NSP3 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NSP3 Conjugated |
| Short name: |
FITC Conjugated, NSP3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, NSP3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16884 |
| Gene: |
SH2D3C |
More about : SH2D3C |
| Long gene name: |
SH2 domain containing 3C |
| Synonyms gene name: |
SH2 domain-containing 3C |
| Locus: |
9q34, 11 |
| Discovery year: |
2001-11-19 |
| GenBank acession: |
AF124251 |
| Entrez gene record: |
10044 |
| Pubmed identfication: |
10187783 |
| RefSeq identity: |
NM_005489 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020717 |