| Long name: |
HRP Conjugated, GPR77 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPR77 |
| Specificity: |
This is a highly specific antibody against GPR77 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GPF77 |
| Gene ID number: |
27202 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
C5L2 is an integral membrane protein that belongs to the Gprotein-coupled receptor 1 family, C5L2 weakly couples to Gi-mediated signaling pathways and is widely expressed in the hippocampus, It is coexpressed with the C5a receptor (C5AR) on polymorphonuclear neutrophils and may modulate the activity of C5AR, Research suggests that C5L2 may be required for the in vitro release of high mobility group box 1 protein (HMGB1), The function of the C5a receptors, a chemotactic and inflammatory peptide, also designated G protein-coupled receptor 77, frontal cortex and liver, hypothalamus, is a receptor for C5a anaphylatoxin chemotactic receptor (C5L2), is still unclear, particularly that of C5L2, pons, Anaphylatoxin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
C5L2 |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
GPR77 Conjugated |
| Short name: |
Conjugated, GPR77 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, G protein-coupled receptor 77 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GPR77 and IDBG-59470 and ENSG00000134830 and 27202, GPR77 and IDBG-639987 and ENSBTAG00000037735 and 522144, Gpr77 and IDBG-146283 and ENSMUSG00000074361 and 319430, Plasma membranes, protein binding, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004944 and C5a anaphylatoxin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0009925 and basal plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0045087 and innate immune response and biological process this GO :0045177 and apical part of cell and cellular component this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0090024 and negative regulation of neutrophil chemotaxis and biological process this GO :1900165 and negative regulation of interleukin-6 secretion and biological process this GO :2000482 and regulation of interleukin-8 secretion and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004944 : C5a anaphylatoxin receptor activity and also this GO :0005515 : protein binding, this GO :0004944 : C5a anaphylatoxin receptor activity, this GO :0005515 : protein binding, G protein-coupled receptor 77 |
| Identity: |
4527 |
| Gene: |
C5AR2 |
More about : C5AR2 |
| Long gene name: |
complement component 5a receptor 2 |
| Synonyms gene: |
GPR77 |
| Synonyms gene name: |
G protein-coupled receptor 77 |
| Locus: |
19q13, 32 |
| Discovery year: |
2000-01-20 |
| GenBank acession: |
AB038237 |
| Entrez gene record: |
27202 |
| Pubmed identfication: |
11165367 |
| RefSeq identity: |
NM_018485 |
| Classification: |
Complement component GPCRs |