| Category: |
Antibody |
| Concentration: |
05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 5 mg/ml in 1X PBS with 0 |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
GPR77 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Primate , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 1-3ug/ml |
| Notes: |
GPR77 antibody titration may be required for optimal results, Provided assay concentrations are suggestions only |
| Added buffer: |
pH 7, 1X Phosphate Buffered Saline (PBS), 4 |
| Intented use: |
This GPR77 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
445269 |
| Purity: |
Purified by protein A Affinity Chromatography |
| Description: |
GPCRs, GPR77 is involved in the complement system of the innate immune response and may signal through the beta-arrestin pathway, It is co-expressed with the C5a receptor on neutrophils and may modulate C5a1 activity, These receptors sense stimuli outside, also called GPRs, and activate internal signal transduction pathways and cellular responses, and possibly act as a decoy receptor, and seven-transmembrane domain receptors, are a large family of receptors with possibly over 800 members, convey the signal across the cell membrane, G protein receptors |
| Immunogen: |
A recombinant protein fragment from the N-terminal region of human GPR77 was used as the immunogen for this antibody |
| Storage: |
Aliquot the GPR77 antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
GPR77 |
| Short name: |
GPR77 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
G protein-coupled receptor 77 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GPR77 and IDBG-59470 and ENSG00000134830 and 27202, GPR77 and IDBG-639987 and ENSBTAG00000037735 and 522144, Gpr77 and IDBG-146283 and ENSMUSG00000074361 and 319430, Plasma membranes, protein binding, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004944 and C5a anaphylatoxin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0009925 and basal plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0045087 and innate immune response and biological process this GO :0045177 and apical part of cell and cellular component this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0090024 and negative regulation of neutrophil chemotaxis and biological process this GO :1900165 and negative regulation of interleukin-6 secretion and biological process this GO :2000482 and regulation of interleukin-8 secretion and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004944 : C5a anaphylatoxin receptor activity and also this GO :0005515 : protein binding, this GO :0004944 : C5a anaphylatoxin receptor activity, this GO :0005515 : protein binding, G protein-coupled receptor 77 |
| Identity: |
4527 |
| Gene: |
C5AR2 |
More about : C5AR2 |
| Long gene name: |
complement component 5a receptor 2 |
| Synonyms gene: |
GPR77 |
| Synonyms gene name: |
G protein-coupled receptor 77 |
| Synonyms: |
C5L2 |
| Locus: |
19q13, 32 |
| Discovery year: |
2000-01-20 |
| GenBank acession: |
AB038237 |
| Entrez gene record: |
27202 |
| Pubmed identfication: |
11165367 |
| RefSeq identity: |
NM_018485 |
| Classification: |
Complement component GPCRs |