| Long name: |
FITC Conjugated, GNS/Glucosamine 6 sulfatase Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GNS/Glucosamine 6 sulfatase |
| Specificity: |
This is a highly specific antibody against GNS/Glucosamine 6 sulfatase |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GNS/Glucosamine 6 sulfatase |
| Gene ID number: |
2799 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A member of the sulfatase family, GNS assists in the catabolism of heparin, GNS deficiency results in an autosomal recessive lysosomal storage disorder known as mucopolysaccharidosis type IIID (Sanfilippo D syndrome), GNS is encoded by a gene mapping to human chromosome 12q14, Subject to post-translational internal peptidase cleavage, and binds calcium as a cofactor, which is characterized by mild somatic disease and severe degeneration of the central nervous system, 2 and mouse chromosome 10 D2, GNS is a 552 amino acid lysosomal enzyme that hydrolyzes the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate and heparan sulfate |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GNS/Glucosamine 6 sulfatase Conjugated |
| Short name: |
FITC Conjugated, GNS/Glucosamine 6 sulfatase Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GNS/Glucosamine 6 sulfatase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4422 |
| Gene: |
GNS |
More about : GNS |
| Long gene name: |
glucosamine (N-acetyl)-6-sulfatase |
| Synonyms name: |
Sanfilippo disease IIID N-acetylglucosamine-6-sulfatase |
| Locus: |
12q14, 3 |
| Discovery year: |
1988-06-09 |
| Entrez gene record: |
2799 |
| Classification: |
Sulfatases |
| Havana BLAST/BLAT: |
OTTHUMG00000168819 |