| Catalog number: | GENTAUR-58be5da24dc0b |
|---|---|
| Price: | 304 € |
| Supplier: | MBS Polyclonals |
| Product name: | Anti-GNS/Glucosamine 6 sulfatase, ALEXA Fluor 594 |
| Quantity: | 50ug |
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| Type: | Conjugated Primary Antibody |
|---|---|
| Conjugated with: | 594, ALEXA FLUOR® |
| Host organism: | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: | GNS/Glucosamine 6 sulfatase |
| Specificity: | This antibody reacts specifically with GNS/Glucosamine 6 sulfatase |
| Modification: | No modification has been applied to this antibody |
| Modification site: | None |
| Clonality: | Polyclonal Antibody |
| Clone: | Polyclonal Antibodies |
| Concentration: | 1ug per 1ul |
| Antigen Source: | KLH conjugated synthetic peptide derived from human GNS/Glucosamine 6 sulfatase |
| Gene ID: | 2799 |
| Applications: | IF(IHC-P) |
| Applications with corresponding dilutions: | IF(IHC-P)(1:50-200) |
| Cross reactive species: | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: | A member of the sulfatase family, GNS assists in the catabolism of heparin, GNS deficiency results in an autosomal recessive lysosomal storage disorder known as mucopolysaccharidosis type IIID (Sanfilippo D syndrome), GNS is encoded by a gene mapping to human chromosome 12q14, Subject to post-translational internal peptidase cleavage, and binds calcium as a cofactor, which is characterized by mild somatic disease and severe degeneration of the central nervous system, 2 and mouse chromosome 10 D2, GNS is a 552 amino acid lysosomal enzyme that hydrolyzes the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate and heparan sulfate |
| Purification method: | Purified by Protein A |
| Storage: | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: | 590nm/617nm |
| Also known as: | GNS/Glucosamine 6 sulfatase Antibody |
| Other name: | Anti-GNS/Glucosamine 6 sulfatase |
| Advisory: | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: | For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | GNS/Glucosamine 6 sulfatase |
| Short name: | Fluor 594, Anti-GNS/Glucosamine 6 sulfatase |
| Label: | ALEXA |
| Alternative name: | ALEXA Fluor 594, antibody to-GNS/Glucosamine 6 sulfatase |
| Identity: | 4422 |
| Gene: | GNS | More about : GNS |
| Long gene name: | glucosamine (N-acetyl)-6-sulfatase |
| Synonyms name: | Sanfilippo disease IIID N-acetylglucosamine-6-sulfatase |
| Locus: | 12q14, 3 |
| Discovery year: | 1988-06-09 |
| Entrez gene record: | 2799 |
| Classification: | Sulfatases |
| Havana BLAST/BLAT: | OTTHUMG00000168819 |
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