| Long name: |
FITC Conjugated, GM2A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GM2A |
| Specificity: |
This is a highly specific antibody against GM2A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
160-193/193 |
| Subcellular location: |
Lysosome |
| Source: |
KLH conjugated synthetic peptide derived from human GM2A/SAP3 |
| Gene ID number: |
2760 |
| Swiss Prot: |
P17900 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds gangliosides and stimulates ganglioside GM2 degradation, GM2A also exhibits some calcium-independent phospholipase activity (By similarity), It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3, It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A, The large binding pocket can accommodate several single chain phospholipids and fatty acids |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
SAP-3 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GM2A Conjugated |
| Short name: |
FITC Conjugated, GM2A Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GM2A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4367 |
| Gene: |
GM2A |
More about : GM2A |
| Long gene name: |
GM2 ganglioside activator |
| Synonyms gene name: |
GM2 ganglioside activator protein |
| Synonyms name: |
cerebroside sulfate activator protein sphingolipid activator protein 3 |
| Locus: |
5q33, 1 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
2760 |
| Pubmed identfication: |
115863 1915857 |
| RefSeq identity: |
NM_000405 |
| Havana BLAST/BLAT: |
OTTHUMG00000130124 |
| Locus Specific Databases: |
GM2A Locus Database |