| Long name: |
Biotin Conjugated, GM2A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GM2A |
| Specificity: |
This is a highly specific antibody against GM2A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
160-193/193 |
| Subcellular location: |
Lysosome |
| Source: |
KLH conjugated synthetic peptide derived from human GM2A/SAP3 |
| Gene ID number: |
2760 |
| Swiss Prot: |
P17900 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds gangliosides and stimulates ganglioside GM2 degradation, GM2A also exhibits some calcium-independent phospholipase activity (By similarity), It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3, It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A, The large binding pocket can accommodate several single chain phospholipids and fatty acids |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
SAP-3 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GM2A Conjugated |
| Short name: |
Conjugated, GM2A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, GM2A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4367 |
| Gene: |
GM2A |
More about : GM2A |
| Long gene name: |
GM2 ganglioside activator |
| Synonyms gene name: |
GM2 ganglioside activator protein |
| Synonyms name: |
cerebroside sulfate activator protein sphingolipid activator protein 3 |
| Locus: |
5q33, 1 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
2760 |
| Pubmed identfication: |
115863 1915857 |
| RefSeq identity: |
NM_000405 |
| Havana BLAST/BLAT: |
OTTHUMG00000130124 |
| Locus Specific Databases: |
GM2A Locus Database |